Epidemiology
- Heart failure (HF) presents a significant healthcare challenge, leading to increased resource utilization and costs.
- Despite advancements in therapies, morbidity and mortality rates persist at high levels.
- HF accounts for a substantial portion of hospitalizations, particularly among individuals over 65, constituting 1-2% of all hospital admissions in the Western world.
- The prevalence of HF ranges between 1% and 3% in the general adult population in industrialized countries and is projected to rise.

Heart failure affects
>64 million
people worldwide

Heart failure patients have
60%
survival at 5 years

50%
of patients with HF have HFrEF
References
- Bragazzi NL et al. Eur J Prev Cardiol. 2021;28:1682-90;
- Rubio R et al. BMJ Open. 2021;11:e053216;
- Major K et al. Cardiol J. 2024;31:156-67;
- Johansson I et al. Circulation. 2021;143:2129-42;
- Savarese G et al. Cardiovasc Res. 2023;118:3272-87;
- Khan MS et al. Nat Rev Cardiol. 2024;21:717-34;
- Ketabi M et al. Curr Cardiol Rep. 2024;26:1113-22